Mica has been proven to have anticancer
effects, however, there is not much data available on its
efficacy and treating mechanism. In Ayurveda- an Indian
system of medicine, a medicine named ‘Abhrak bhasma’,
is incinerated mica-based nano-material being used for
centuries to treat various respiratory conditions and lungrelated diseases. Nanoparticles are proven to have
advantages in cancer treatment. The purpose of this study
was to examine ‘ Abhrak Bhasma’ induced cytotoxicity on
the A549 cell line.
Method - Cytotoxicity was measured by MTT assay on
A549 cell line
Result - Mica nanoparticles at up to 200µ/mL for 24 hours
showed concentration dependant cytotoxic activity. The
calculated IC50 value was 168.60µg/mL
Conclusion - This is the first report showing that Abhrak
bhasma or mica nanoparticles induce cytotoxicity in A459
cells.