A Systematic Review on the Comparison of Molecular Gene Editing Tools


Authors : Jannat Rahim; Sabahat Gulzar; Rohama Zahid; Khushbakht Rahim

Volume/Issue : Volume 6 - 2021, Issue 8 - August

Google Scholar : http://bitly.ws/9nMw

Scribd : https://bit.ly/2WVFecx

The advancement and latest technologies used for genome editing has opened the door of targeting and altering the genomic sequences, depending upon the bacterial nucleases, in almost all eukaryotic cells. Genomic editing has helped the scientists in understanding the contribution of genetics in studying pathological process of many diseases by creating accurate animal and cellular models. This technique has shown extraordinary potential and provided latest approaches from basic research to advance biomedical and biotechnological research. The idea of gene editing technology has reached the clinical practice phase after the discovery of programable gene editors like Zinc Finger Nucleases (ZFN), Transcription Activator Like Effector Nucleases (TALENs) and Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)–Casassociated nuclease. This review will discuss all the three strategies (ZFN, TALENS, CRISPR/case system) used for genome editing and their application against the diseases as well as their mode of action and delivery methods.

Keywords : Genome editing; Zinc Finger Nucleases (ZFN); Transcription Activator Like Effector Nucleases (TALENs); styling; Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)–Cas9.

CALL FOR PAPERS


Paper Submission Last Date
31 - May - 2022

Paper Review Notification
In 1-2 Days

Paper Publishing
In 2-3 Days

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe