Authors :
CM Amatorio; R Cacacho; EM Delino; LK Barretto; MG Acal; G Estorico
Volume/Issue :
Volume 9 - 2024, Issue 11 - November
Google Scholar :
https://tinyurl.com/4e35wnpv
Scribd :
https://tinyurl.com/59zacay8
DOI :
https://doi.org/10.5281/zenodo.14351342
Abstract :
Bacterial pathogens such as Chlamydia
trachomatis, Neisseria gonorrhoeae, Mycoplasma
genitalium, Treponema pallidum, Granuloma inguinale,
and Ureaplasma urealyticum play significant roles in
sexually transmitted diseases (STDs), posing risks of
severe reproductive complications. This systematic
review aimed to collect and analyze data on bacterial
pathogens, focusing on their gender-specific infection
rates, age prevalence, annual infection rates,
epidemiological patterns, clinical manifestations,
diagnostic methods, complications, and treatment
approaches. A comprehensive review was conducted from
2015 to 2024, covering epidemiological patterns,
diagnostic practices, and treatment protocols associated
with these pathogens. Findings reveal that Chlamydia
trachomatis affects 60% women and 40% men, primarily
among those aged 15-49, with 128.5 million new infections
annually. Neisseria gonorrhoeae infects 43% women and
57% men in the 15-24 age group, with 82 million new
cases annually. Mycoplasma genitalium and Treponema
pallidum affect predominantly young adults, with
infection rates of 48% and 52% in men and women,
respectively, and over 3 million new infections each year.
Other notable findings include high prevalence rates of
Granuloma inguinale in men (85-90%), and Ureaplasma
urealyticum in women (67.9%). This study underscores
the importance of accurate pathogen identification and
epidemiological insight in preventing and treating STDs,
which remain a major public health concern worldwide.
Keywords :
Epidemiological Patterns, Infections, Prevalence, Reproductive Complications, Risk.
References :
- Belda, W., Junior. (2020). Donovanosis. Anais Brasileiros De Dermatologia, 95(6), 675–683. https://doi.org/10.1016/j.abd.2020.07.002
- Chemaitelly, H., Majed, A., Abu-Hijleh, F., Blondeel, K., Matsaseng, T. C., Kiarie, J., Toskin, I., & Abu-Raddad, L. J. (2020). Global epidemiology of Neisseria gonorrhoeae in infertile populations: A systematic review, meta-analysis, and meta-regression. Sexually Transmitted Infections. https://doi.org/10.1136/sextrans-2020-054515
- Huai, P., Li, F., Chu, T., Liu, D., Liu, J., & Zhang, F. (2020). Prevalence of genital Chlamydia trachomatis infection in the general population: A meta-analysis. BMC Infectious Diseases, 20(589). https://doi.org/10.1186/s12879-020-05307-w
- Morris, S. R. (2023a, January 10). Syphilis. MSD Manual Professional Edition. https://www.msdmanuals.com/professional/infectious-diseases/sexually-transmitted-infections-stis/syphilis
- Morris, S. R. (2023b, January 10). Granuloma inguinale. MSD Manual Professional Edition. https://www.msdmanuals.com/professional/infectious-diseases/sexually-transmitted-infections-stis/granuloma-inguinale
- Pam Sonnenberg, Catherine A. Ison, Soazig Clifton, Nigel Field, Clare Tanton, Kate Soldan, Simon Beddows, Sarah Alexander, Rumena Khanom, Pamela Saunders, Andrew J. Copas, Kaye Wellings, Catherine H. Mercer, Anne M. Johnson. (2015). Epidemiology of Mycoplasma genitalium in British men and women aged 16–44 years: evidence from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). International Journal of Epidemiology, 44(6), 1982–1994. https://doi.org/10.1093/ije/dyv194
- Rodrigues, R., Sousa, C., & Vale, N. (2022). Chlamydia trachomatis as a Current Health Problem: Challenges and Opportunities. Diagnostics, 12(8), 1795. https://doi.org/10.3390/diagnostics12081795
- Song, J., Wu, X., Kong, Y., Jin, H., Yang, T., Xie, X., & Zhang, J. (2022). Prevalence and antibiotic resistance of Ureaplasma species and Mycoplasma hominis in Hangzhou, China, from 2013 to 2019. Frontiers in Microbiology, 13, 982429.
- Unemo, M., Seifert, H. S., Hook, E. W., Hawkes, S., Ndowa, F., & Dillon, J. R. (2019). Gonorrhoea. Nature Reviews Disease Primers, 5(1). https://doi.org/10.1038/s41572-019-0128-6
- Winge, Jackie. (2023, December 5). Mycoplasma genitalium | Symptoms, Causes and Complications. Clarewell Clinics. https://clarewellclinics.co.uk/sti/mycoplasma-genitalium/
Bacterial pathogens such as Chlamydia
trachomatis, Neisseria gonorrhoeae, Mycoplasma
genitalium, Treponema pallidum, Granuloma inguinale,
and Ureaplasma urealyticum play significant roles in
sexually transmitted diseases (STDs), posing risks of
severe reproductive complications. This systematic
review aimed to collect and analyze data on bacterial
pathogens, focusing on their gender-specific infection
rates, age prevalence, annual infection rates,
epidemiological patterns, clinical manifestations,
diagnostic methods, complications, and treatment
approaches. A comprehensive review was conducted from
2015 to 2024, covering epidemiological patterns,
diagnostic practices, and treatment protocols associated
with these pathogens. Findings reveal that Chlamydia
trachomatis affects 60% women and 40% men, primarily
among those aged 15-49, with 128.5 million new infections
annually. Neisseria gonorrhoeae infects 43% women and
57% men in the 15-24 age group, with 82 million new
cases annually. Mycoplasma genitalium and Treponema
pallidum affect predominantly young adults, with
infection rates of 48% and 52% in men and women,
respectively, and over 3 million new infections each year.
Other notable findings include high prevalence rates of
Granuloma inguinale in men (85-90%), and Ureaplasma
urealyticum in women (67.9%). This study underscores
the importance of accurate pathogen identification and
epidemiological insight in preventing and treating STDs,
which remain a major public health concern worldwide.
Keywords :
Epidemiological Patterns, Infections, Prevalence, Reproductive Complications, Risk.