A Synthesis and Biological Evaluation of Indole Derivatives


Authors : Mamta H. Chauhan; Nilesh L. Solanki; Dhananjay K. Pandya

Volume/Issue : Volume 7 - 2022, Issue 6 - June

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3PmtHJb

DOI : https://doi.org/10.5281/zenodo.6865058

Abstract : Oxoindolines are interesting heterocyclic compounds which show diverse biological significance. In this oxoindolines was prepared by one-pot condensation reaction of isatin, dimedone, and various active methylene using piperidine as a basic catalyst and solvent as methanol, under stirring at ambient temperature. The final products were characterized by FT-IR spectroscopy, Massspectroscopy, 1H NMR-spectroscopy and 13C NMRspectroscopy.

Keywords : MCRS, Isatin, Dimedone, Oxoindolines, Antimicrobial Estimation.

Oxoindolines are interesting heterocyclic compounds which show diverse biological significance. In this oxoindolines was prepared by one-pot condensation reaction of isatin, dimedone, and various active methylene using piperidine as a basic catalyst and solvent as methanol, under stirring at ambient temperature. The final products were characterized by FT-IR spectroscopy, Massspectroscopy, 1H NMR-spectroscopy and 13C NMRspectroscopy.

Keywords : MCRS, Isatin, Dimedone, Oxoindolines, Antimicrobial Estimation.

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