Breast cancer is a disease in which cells in the breast grow out of control. It can spread outside the breast through blood vessels and through lymph nodes. There is rapid increase in the incidence between the age 35 to 50 years and secondary rise in frequency after 65 years of age. In the world wide Over 1,00,000 new breast cancer patients are estimated annually in India. Cancer prevalence in India is estimated around 2.5 million with over 0.8 million new cases. Causes and risk factors of breast cancer are genetic factor, previous breast cancer, null parity, high socioeconomic status, early menarche, late menopause, diet high in total fat. Treatment of breast cancer requires mastectomy, lymph node removal, chemotherapy and radiation therapy based on level of lymph nodes involved. A quantitative approach was adopted to assess the knowledge regarding pink ribbon among female students. The investigator selected 30 female students of PUC Science group studying in Yenepoya school, Mangaluru. Non probability purposive sampling was used to select the desired size of female students. The study findings shows that 7(23%) students having moderate knowledge,23(77%) students having inadequate knowledge and no samples having adequate knowledge. The study findings revealed that variables such as age in years, stream of study, age of menarche , past history of breast cancer in the family, source of information were significantly associated with knowledge of female students regarding pink ribbon at 0.05 levels. Hence it is concluded that most of them having inadequate knowledge regarding pink ribbon.