The term "CAD" stands for "coronary artery
disease." The majority of deaths are caused by it
globally. It is a disorder when the heart can no longer
adequately pump blood to the body's tissues because to a
build-up of plaque in the blood arteries (a condition
known as atherosclerosis). Heart failure can result from
this condition. The main risk factors for CAD are
hypertension, dyslipidemia, obesity, inactivity, and
elevated levels of C-reactive protein and blood sugar.
Medical, surgical, and herbal treatments are currently
available. While this treatment can increase a patient's
quality of life and chances of survival, it has no effect on
the speed of the disease. Clinical researchers have been
working with biotechnology and tissue engineering to
identify new therapeutic approaches that may result in
stem cell therapy, nanotechnology, gene therapy
treatments, and robots. The primary goals of these
innovative methods are to lessen and heal myocardial
damage and enhance blood flow to the ischemic heart's
myocardium. Clinical studies on stem cell-based therapy
have produced effective and hopeful outcomes, including
decreased myocardial cell death, decreased scarring,
increased angiogenesis, and improved heart function.
The development of a nanotechnology method that aids
in targeted drug distribution, boosts therapeutic
effectiveness, and lengthens the duration of action. A
novel approach is gene therapy, which promotes
angiogenesis. These emerging treatments have the
potential to be potent substitutes for current treatment
modalities thanks to the significant and ongoing work of
researchers and doctors around the world.
Atherosclerosis, Coronary artery disease, stem cell, Nanotechnology, Gene therapy.