Authors :
Jeevandeep Mishra; Dr. Shiv Hardenia; Dr. D.K. Jain
Volume/Issue :
Volume 8 - 2023, Issue 6 - June
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/bx3seteh
DOI :
https://doi.org/10.5281/zenodo.8047479
Abstract :
The design of the oral drug delivery system,
which is still the dominant method of drug delivery
despite a number of drawbacks, must take into account
the ease of administration and increased patient
compliance. Due to the insufficient development of the
muscular and neurological systems in children, as well as
cases of elderly individuals with Parkinson's disease or
hand tremors, fast-dissolving tablets have become one of
the most well-liked and widely recognised dose forms.
Today's solid dosage forms, such as capsules and tablets,
are dealing with issues like dysphagia, which leads to
numerous instances. In mouth dissolving tablets
superdisintegrants are incorporated in right amount for
quick disintegration with improved bioavailability.FDTs
either disintegrate or dissolve rapidly in saliva without
the need for water. Real fast-dissolving tablets are made
to dissolve in saliva incredibly quicklyin less than 60
seconds. By using different processes, such as direct
compression, tablet moulding, freeze drying, and spray
drying nanonization, one can create a drug delivery
system that dissolves quickly.This article provides a brief
description of FDTs, including their definition, benefits,
uses, key characteristics, drawbacks, problems in their
development, Technology used for manufacturing of fast
dissolving tablets, Common excipients used in fast
dissolving tablets and commercially available fastdissolving tablet formulations.
Keywords :
Oral drug delivery, Fast dissolving tablet, Superdisintegrants, Bioavailability, Technology.
The design of the oral drug delivery system,
which is still the dominant method of drug delivery
despite a number of drawbacks, must take into account
the ease of administration and increased patient
compliance. Due to the insufficient development of the
muscular and neurological systems in children, as well as
cases of elderly individuals with Parkinson's disease or
hand tremors, fast-dissolving tablets have become one of
the most well-liked and widely recognised dose forms.
Today's solid dosage forms, such as capsules and tablets,
are dealing with issues like dysphagia, which leads to
numerous instances. In mouth dissolving tablets
superdisintegrants are incorporated in right amount for
quick disintegration with improved bioavailability.FDTs
either disintegrate or dissolve rapidly in saliva without
the need for water. Real fast-dissolving tablets are made
to dissolve in saliva incredibly quicklyin less than 60
seconds. By using different processes, such as direct
compression, tablet moulding, freeze drying, and spray
drying nanonization, one can create a drug delivery
system that dissolves quickly.This article provides a brief
description of FDTs, including their definition, benefits,
uses, key characteristics, drawbacks, problems in their
development, Technology used for manufacturing of fast
dissolving tablets, Common excipients used in fast
dissolving tablets and commercially available fastdissolving tablet formulations.
Keywords :
Oral drug delivery, Fast dissolving tablet, Superdisintegrants, Bioavailability, Technology.
