Authors :
Urja M. Mehta; Jeet M. Gajjar
Volume/Issue :
Volume 9 - 2024, Issue 7 - July
Google Scholar :
https://tinyurl.com/ybcef2wn
Scribd :
https://tinyurl.com/yc59an8v
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24JUL311
Abstract :
Polyarteritis nodosa (PAN) is a rare systemic
vasculitis affecting small and medium-sized arteries. While
PAN primarily involves arterial vessels, its association
with venous thromboembolic events such as pulmonary
embolism (PE) and deep vein thrombosis (DVT) and their
consequences such as cardiac arrest are infrequently
reported. Understanding the clinical presentation and
management of PAN complicated by PE, and cardiac
arrest is crucial for optimizing patient care. We present a
case of a patient with a history of polyarteritis nodosa
(PAN) who presented with a cardiac arrest complicated by
pulmonary embolism (PE). Through meticulous analysis
and multidisciplinary intervention, the patient’s condition
was stabilized, shedding light on the complexities of
managing such rare and life-threatening complications
within the context of PAN. This case underscores the
importance of prompt recognition, comprehensive
evaluation, and targeted therapeutic interventions in
navigating the intricate interplay of vasculitis,
thromboembolic events, and cardiac complications in
patients with Polyarteritis nodosa.
Keywords :
Polyarteritis Nodosa, Cardiac Arrest, Pulmonary Embolism, Vasculitis
References :
- De Virgilio A, Greco A, Magliulo G, Gallo A, Ruoppolo G, Conte M, et al. Polyarteritis nodosa: A contemporary overview. Autoimmunity Reviews [Internet]. 2016 Jun [cited 2024 Mar 28];15(6):564–70. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1568997216300416
- High risk of pulmonary embolism in patients with autoimmune disorders. Nat Rev Cardiol [Internet]. 2012 Feb [cited 2024 Mar 28];9(2):66–66. Available from: https://www.nature.com/articles/nrcardio.2011.199
- Ungprasert P, Koster MJ, Thongprayoon C, Warrington KJ. Risk of venous thromboembolism among patients with vasculitis: a systematic review and meta-analysis. Clin Rheumatol [Internet]. 2016 Nov [cited 2024 Mar 28];35(11):2741–7. Available from: http://link.springer.com/10.1007/s10067-016-3394-7
- Schrader ML, Hochman JS, Bulkley BH. The heart in polyarteritis nodosa: A clinicopathologic study. American Heart Journal [Internet]. 1985 Jun [cited 2024 Mar 28];109(6):1353–9. Available from: https://linkinghub.elsevier.com/retrieve/pii/0002870385903655
- Lai J, Zhao L, Zhong H, Zhou J, Guo X, Xu D, et al. Characteristics and outcomes of coronary artery involvement in polyarteritis nodosa. Canadian Journal of Cardiology [Internet]. 2021 Jun [cited 2024 Mar 28];37(6):895–903. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0828282X20311120
- Bae YD, Choi HJ, Lee JC, Park JJ, Lee YJ, Lee EB, et al. Clinical features of polyarteritis nodosa in korea. J Korean Med Sci [Internet]. 2006 [cited 2024 Mar 28];21(4):591. Available from: https://jkms.org/DOIx.php?id=10.3346/jkms.2006.21.4.591
- Tănăsescu C, Jurcuţ C, Caraiola S, Niţescu D, Copaci I, Jurcuţ R. Endothelial dysfunction in inflammatory rheumatic diseases. Rom J Intern Med. 2009;47(2):103–8.
- Harada Y, Suzuki T, Shinagawa T, Yoshimoto T. Cardiac arrest in a patient with polyarteritis nodosa. Intern Med [Internet]. 2013 [cited 2024 Mar 28];52(24):2759–63. Available from: https://www.jstage.jst.go.jp/article/internalmedicine/52/24/52_52.1090/_article
Polyarteritis nodosa (PAN) is a rare systemic
vasculitis affecting small and medium-sized arteries. While
PAN primarily involves arterial vessels, its association
with venous thromboembolic events such as pulmonary
embolism (PE) and deep vein thrombosis (DVT) and their
consequences such as cardiac arrest are infrequently
reported. Understanding the clinical presentation and
management of PAN complicated by PE, and cardiac
arrest is crucial for optimizing patient care. We present a
case of a patient with a history of polyarteritis nodosa
(PAN) who presented with a cardiac arrest complicated by
pulmonary embolism (PE). Through meticulous analysis
and multidisciplinary intervention, the patient’s condition
was stabilized, shedding light on the complexities of
managing such rare and life-threatening complications
within the context of PAN. This case underscores the
importance of prompt recognition, comprehensive
evaluation, and targeted therapeutic interventions in
navigating the intricate interplay of vasculitis,
thromboembolic events, and cardiac complications in
patients with Polyarteritis nodosa.
Keywords :
Polyarteritis Nodosa, Cardiac Arrest, Pulmonary Embolism, Vasculitis