- Infectious diseases are still a problem crucial to public health, especially in countries develop. Reality shows that in developing countries, the country's order of the primary diseases is still occupied by various infectious diseases that require antibiotic therapy. Research on the quality of antibiotic use in multiple parts, the hospital found 30% to 80% not based on indications. Therefore, the judicious use of antibiotics is essential In addition to implementing good infection control to prevent the development of resistant bacteria in society. This study uses a cross-sectional descriptive design, using retrospective data with a qualitative approach using the Gyssens method and a quantitative approach using the DDD/100 patient-days method. This study uses secondary data retrospectively in the form of medical records of Intensive Care Unit (ICU) patients at the Petala Bumi Regional General Hospital, Riau Province, who were treated from January 1, 2018 to December 31, 2018, and January 1, 2019, to December 31, 2019. Where the percentage of accuracy or not administration of antibiotics. The data obtained will be analyzed quantitatively and presented in an analytical description.

Keywords : Antibiotics, ATC/DDD, Quantitative