A Narrative Review: The Risk Factors and Prevalence of CAUTI Among Patients Admitted in Intensive Care Unit


Authors : Hemlata Lalia; Dr. Reddeppa Sreeraja Kumar; Dr. Rizu Negi

Volume/Issue : Volume 10 - 2025, Issue 11 - November


Google Scholar : https://tinyurl.com/2rf4pxk8

Scribd : https://tinyurl.com/rswnt4vk

DOI : https://doi.org/10.38124/ijisrt/25nov1549

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Abstract : CAUTI is one of the most common healthcare-associated diseases in the world. It mostly affects patients in hospitals who need indwelling urinary catheters. CAUTI results in heightened morbidity, extended hospitalizations, elevated treatment expenses, and the development of multidrug-resistant bacteria. To make patients safer and lower healthcare costs, it's vital to know how often it occurs, what causes it, how microbes spread, and how to stop it.  Method A narrative review was performed to examine articles published in the past decade concerning the prevalence, risk factors, microbiology, and prevention of CAUTI. Databases were examined for full-text research pertaining to adult people (≥18 years). Based on predefined inclusion criteria, 12 eligible studies were included. These studies had cross-sectional, cohort, retrospective, quasi-experimental, laboratory-based, and prospective designs. We collected information from each study regarding the sample characteristics, diagnostic criteria, pathogens identified, and the most significant results.  Results The reported prevalence of CAUTI varied significantly between studies, from 12.5% to 49.1%, with the greatest rates observed in ICU and long-term catheterized patients. The primary risk factors identified were prolonged catheterization, advanced age, female gender, diabetes, and inadequate perineal hygiene. Escherichia coli was always the most common pathogen in microbiological profiles, followed by Klebsiella, Enterococcus, Candida, and Pseudomonas species. Several studies indicated that antimicrobial resistance was very high, with up to 77% of bacteria being resistant to ampicillin and many bacteria being resistant to fluoroquinolones. Intervention-based research indicated that using infection-control bundles can cut CAUTI rates by a large amount (for example, from 20% to 9%). The narrative review concludes that CAUTI continues to be a significant healthcare issue, closely linked to catheter duration, comorbidities, and deficiencies in infection-control methods. The high rate of occurrence and increasing resistance to several drugs show how important it is to enhance hygiene procedures, strengthen surveillance, quickly remove catheters, and create strong antimicrobial stewardship programs. Additional multicentre research and developments, including anti- biofilm catheter coatings and quick diagnostic procedures, are crucial for attaining enduring CAUTI prevention and enhanced patient outcomes.

Keywords : CAUTI, Prevalence, Comorbidities, Tertiary Care Unit, Urinary Catheter.

References :

  1. Hassan, F.A.M., et al. (2025) ‘Catheter-Associated Urinary Tract Infection in Critically Ill Patients: A Randomized Prospective Study Comparing Latex with Latex-Coated Metal Alloy Catheters Available at Cureus, 17(2), e52903. doi:10.7759/cureus.52903.
  2. Vishwajith, Sahkare, R., Rao, K.A., Sangeetha, S. (2021) "A study on catheter-associated urinary tract infections (CAUTI) and the antibiotic sensitivity pattern of uropathogens causing CAUTI from a tertiary care hospital," Available at Indian Journal of Microbiology Research, 8(3), pp. 196–199. doi:10.18231/j.ijmr.2021.040.
  3. Sleziak, J., et al. (2025) "Catheter-associated urinary tract infections in the intensive care unit: Epidemiology and microbiological characteristics,"  Available at PeerJ, 13, e15273. doi:10.7717/peerj.15273.
  4. Rosenthal, V.D. (2024) "Preventing catheter-associated urinary tract infections," Available at International Journal of Infectious Diseases, S1201971224003801. doi:10.1016/j.ijid.2024.01.026.
  5. Shmoury, A.H., et al. (2024) 'Epidemiology and microbiology of catheter-associated urinary tract infections in a tertiary care center in Lebanon',  Available at Journal of Infection and Public Health, 17(4), pp. 567–573. doi:10.1016/j.jiph.2024.02.009.
  6. Hooton, T. M. et al. (2010) 'Diagnosis, Prevention, and Treatment of Catheter-Associated Urinary Tract Infection in Adults: 2009 International Clinical Practice Guidelines', Clinical Infectious Diseases, Available at 50(5), pp. 625–663. doi:10.1086/650482
  7. Kar M. and others Features of Bacterial Colonization and Urinary Tract Infections in Catheterized Individuals. 2022. Available at  https://pubmed.ncbi.nlm.nih.gov/35910826/DOI: 10.1093/mmy/myac094
  8. Latthe PM et al. A review of catheter-associated urinary tract infections. 2024. Available at : https://wjwch.com/catheter-associated-urinary-tract-infections-a-review/
  9. Parihar S. et al. An observational study to assess CAUTI in Northern India. 2022. Available at : https://pmc.ncbi.nlm.nih.gov/articles/PMC10504643/
  10. Mohamed AH. and others Antimicrobial Resistance and Factors Linked to CAUTI. 2022. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8948891/
  11. Saleem M. and others Catheter-Associated Urinary Tract Infection in Intensive Care Units. 2022. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9322978/
  12. Lepori M. A full review of the microbial spectrum in CAUTI. 2024. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11638318
  13. Bagchi I., et al. Microbiological Assessment of CAUTI and Its Correlation with Catheterization Duration. 2015. Available att: https://pjsr.org/WebPages/ArchivesPages/Vol8-2-2015Abs/5.pdf

CAUTI is one of the most common healthcare-associated diseases in the world. It mostly affects patients in hospitals who need indwelling urinary catheters. CAUTI results in heightened morbidity, extended hospitalizations, elevated treatment expenses, and the development of multidrug-resistant bacteria. To make patients safer and lower healthcare costs, it's vital to know how often it occurs, what causes it, how microbes spread, and how to stop it.  Method A narrative review was performed to examine articles published in the past decade concerning the prevalence, risk factors, microbiology, and prevention of CAUTI. Databases were examined for full-text research pertaining to adult people (≥18 years). Based on predefined inclusion criteria, 12 eligible studies were included. These studies had cross-sectional, cohort, retrospective, quasi-experimental, laboratory-based, and prospective designs. We collected information from each study regarding the sample characteristics, diagnostic criteria, pathogens identified, and the most significant results.  Results The reported prevalence of CAUTI varied significantly between studies, from 12.5% to 49.1%, with the greatest rates observed in ICU and long-term catheterized patients. The primary risk factors identified were prolonged catheterization, advanced age, female gender, diabetes, and inadequate perineal hygiene. Escherichia coli was always the most common pathogen in microbiological profiles, followed by Klebsiella, Enterococcus, Candida, and Pseudomonas species. Several studies indicated that antimicrobial resistance was very high, with up to 77% of bacteria being resistant to ampicillin and many bacteria being resistant to fluoroquinolones. Intervention-based research indicated that using infection-control bundles can cut CAUTI rates by a large amount (for example, from 20% to 9%). The narrative review concludes that CAUTI continues to be a significant healthcare issue, closely linked to catheter duration, comorbidities, and deficiencies in infection-control methods. The high rate of occurrence and increasing resistance to several drugs show how important it is to enhance hygiene procedures, strengthen surveillance, quickly remove catheters, and create strong antimicrobial stewardship programs. Additional multicentre research and developments, including anti- biofilm catheter coatings and quick diagnostic procedures, are crucial for attaining enduring CAUTI prevention and enhanced patient outcomes.

Keywords : CAUTI, Prevalence, Comorbidities, Tertiary Care Unit, Urinary Catheter.

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Paper Submission Last Date
31 - December - 2025

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