Authors : Atinuke Oluwabukola Kalada Richard; Ibukun D. Oyinloye

Volume/Issue : Volume 11 - 2026, Issue 10 - October

Google Scholar : https://tinyurl.com/54pfc8vz

DOI : https://doi.org/10.38124/ijisrt/26Oct1003

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : Background: Atrial myxoma is the most common benign primary cardiac tumor and may occur sporadically or as part of a familial syndrome. Although clinical manifestations vary, neurological complications secondary to tumor embolization are relatively uncommon. We report a case of atrial myxoma presenting as acute ischemic stroke in a young, previously healthy adult.  Case Presentation: A 25-year-old previously healthy man presented with a 4-day history of acute neurologic deficit. Non-contrast computed tomography of the brain demonstrated multiple acute ischemic infarcts involving the left cerebral hemisphere. Echocardiography subsequently revealed a large, mobile, hyperechoic intracardiac mass, highly suggestive of a left atrial myxoma and providing a likely source of cardioembolic stroke.  Conclusion: This case demonstrates the importance of prompt cardiac evaluation in young patients presenting with unexplained ischemic stroke, as early identification of an intracardiac mass may facilitate appropriate management and prevent recurrent embolic events.  Summary: Atrial Myxoma is the most common benign primary cardiac tumor that rarely presents with neurologic deficits. We present a case of a 25-year-old male with acute-onset neurological deficits. Echo revealed a large mass highly suggestive of atrial myxoma. This case highlights the importance of prompt cardiac evaluation in young patients with unexplained ischemic stroke to identify intracardiac sources and prevent recurrence.

Keywords : Atrial Myxoma; Ischemic Stroke; Cardioembolic Stroke; Young Adult; Left Atrial Mass; Systemic Embolization; Echocardiography.

References :

1. WHO Classification of Tumours Editorial Board. Thoracic Tumours. 5th edition. Lyon (France): International Agency for Research on Cancer; 2021. Volume 5:
2. Okongwu CC, Olaofe OO. Cardiac Myxoma: a comprehensive review. J Cardiothoracic Surg. 2025 Mar 13.20 (1):151 [QxMD MEDLINE Link].[Full Text].
3. Hasan M, Abdelmaseih R, Faluk M, Chacko J, Nasser H. Atria Myxoma, a rare cause of sudden cardiac death: a case report and review of literature. Cureus. 2020 Jan 19. 12(1):e6704. [QxMD MEDLINE Link].[Full Text].
4. Manche N, Mercer Mk, Baruah D. Diagnosis and Treatment of Cardiac Myxoma. Cureus 2023 May 15 (5):e339148 [QxMD MEDLINE Link].[Full Text].
5. Wen XY, Chen YM, Yu LL, et al. Neurological manifestations of atrial myxoma: A retrospective analysis. Oncol Lett. 2018 Oct. 16(4):4635-9. [QxMD MEDLINE Link].[Full Text].
6. Watanabe Y, Sakamoto SI, Motoda N, Maeda M, Murata T, Ishii Y. Staged Cesarean and Cardiac Surgery for Recurrent Left Atrial Myxofibrosarcoma in Pregnancy. JACC Case Rep. 2026 Aug 5. 31 (31):108770. [QxMD MEDLINE Link].[Full Text].
7. Rahouma M, Mohsen H, Morsi M, Khairallah S, Azab L, Abdelhemid M, et al. Prevalence, Diagnosis, and Treatment of Cardiac Tumors: A Narrative Review. J Clin Med. 2025 May 13. 14 (10):[QxMD MEDLINE Link].[Full Text].
8. Patil NP, Dutta N, Satyarthy S, Geelani MA, Kumar Satsangi D, Banerjee A. Cardiac myxomas: experience over one decade. J Card Surg. 2011 Jul. 26(4):355-9. [QxMD MEDLINE Link].
9. Baikoussis NG, Papakonstantinou NA, Dedeilias P, et al. Cardiac tumors: a retrospective multicenter institutional study. J BUON. 2015 Jul-Aug. 20(4):1115-23. [QxMD MEDLINE Link].
10. Shah IK, Dearani JA, Daly RC, et al. Cardiac myxomas: a 50-year experience with resection and analysis of risk factors for recurrence. Ann Thorac Surg. 2015 Aug. 100(2):495-500. [QxMD MEDLINE Link]. 11. Manche N, Mercer MK, Baruah D. Diagnosis and Treatment of Cardiac Myxoma. Cureus. 2023 May. 15 (5):e39148. [QxMD MEDLINE Link].[Full Text].