NHMIS in Nigeria is a design established to collect, store, process and manage health care data in an effective and efficient manner in such a way that it will enhance health care delivery. NHMIS involves collection, storage and the transfer of a patient’s EMedical record, An health institution supporting health care policy decisions. National Health Management Information Systems. (NHMIS) promotes efficacious and valid services within hospital settings. NHMIS was introduced in Nigeria precisely 2006 which encompass all health information system. The achievement of NHMIS becomes a mirage due to challenges and problems faced with by health institutions. Be that as it may, it's imperative to have knowledge about determinants for successful implementation to make sure there is qualitative NHMIS. The successfulness of the implementation process of NHMIS is reliant on factors ranging from Technological, personnel and Institutional factors. Any problem relating to heath institutions if pointed out should avert poor implementation in the long run. Thus, this article will review problems of health institution factors affecting the efficacy of NHMIS while considering plans needed to forestall problems earlier identified.