Authors :
Shirvadkar Divyashree M; Dr. Prashanth A S
Volume/Issue :
Volume 5 - 2020, Issue 8 - August
Google Scholar :
http://bitly.ws/9nMw
Scribd :
https://bit.ly/3jUAtWd
DOI :
10.38124/IJISRT20AUG699
Abstract :
The change in living habits due to increasing
popularity of fast foods, sedentary lifestyle have given
rise to lifestyle disorders and Non Alcoholic
Steatohepatitis is one among them. Non Alcoholic
Steatohepatitis (NASH) is a spectrum of Non Alcoholic
Fatty Liver Disease (NAFLD) characterized by the
presence of hepatic steatosis and inflammation with
hepatocyte injury (ballooning) with or without
fibrosis.There is no direct reference to NASH in
Ayurvedic literature but based on the etiopathogenesis,
signs and symptoms it can be correlated to
Yakritodara.NASH has no FDA approved therapeutics,
so, it is need of the hour to search an effective
hepatoprotective remedy from Ayurvedic treasure of
therapeutics. Hence, the present study was designed as
cross over single blind clinical study with the objectives
of evaluating the combined efficacy of
Amapachana,Ruksha virechana and Shamanoushadhi
with Lashuna Erandadi Kashaya and Patolamooladi
Kashaya in the management of NASH. Overall study
showed marked improvement in 60% of cases and
Moderate improvement in 26.66%. Hence,it can be
concluded that the combined effect of therapy with
Amapachana,Ruksha virechana and Shamanoushadhis
(Lashuna Erandadi Kashaya and Patolamooladi
Kashaya) has shown a significant role in relieving the
signs and symptoms of subjects diagnosed with Non
Alcoholic Steatohepatitis
Keywords :
Lifestyle disorders,NASH, Yakritodara, Virechana,Lashuna Erandadi Kashaya, Patolamooladi Kashaya.
The change in living habits due to increasing
popularity of fast foods, sedentary lifestyle have given
rise to lifestyle disorders and Non Alcoholic
Steatohepatitis is one among them. Non Alcoholic
Steatohepatitis (NASH) is a spectrum of Non Alcoholic
Fatty Liver Disease (NAFLD) characterized by the
presence of hepatic steatosis and inflammation with
hepatocyte injury (ballooning) with or without
fibrosis.There is no direct reference to NASH in
Ayurvedic literature but based on the etiopathogenesis,
signs and symptoms it can be correlated to
Yakritodara.NASH has no FDA approved therapeutics,
so, it is need of the hour to search an effective
hepatoprotective remedy from Ayurvedic treasure of
therapeutics. Hence, the present study was designed as
cross over single blind clinical study with the objectives
of evaluating the combined efficacy of
Amapachana,Ruksha virechana and Shamanoushadhi
with Lashuna Erandadi Kashaya and Patolamooladi
Kashaya in the management of NASH. Overall study
showed marked improvement in 60% of cases and
Moderate improvement in 26.66%. Hence,it can be
concluded that the combined effect of therapy with
Amapachana,Ruksha virechana and Shamanoushadhis
(Lashuna Erandadi Kashaya and Patolamooladi
Kashaya) has shown a significant role in relieving the
signs and symptoms of subjects diagnosed with Non
Alcoholic Steatohepatitis
Keywords :
Lifestyle disorders,NASH, Yakritodara, Virechana,Lashuna Erandadi Kashaya, Patolamooladi Kashaya.