Authors : Milly Gladys Iteriteka; Lakavath Sunil Kumar

Volume/Issue : Volume 9 - 2024, Issue 8 - August

Google Scholar : https://tinyurl.com/575mkbyx

Scribd : https://tinyurl.com/2sd3jk6n

DOI : https://doi.org/10.38124/ijisrt/IJISRT24AUG145

Abstract : Injectable solutions are sterile, pyrogen- limited preparations intended to be administered parenterally. Solutions are clear, transparent, and free from particulate matter. Formulations are designed with suitable excipients. They are safe and effective in drug delivery systems. Injectable preparations may be packaged in prefilled syringes, vials, collapsible bag systems, or flexible plastic containers, and packaged with or without the addition of a secondary protective container. They come in packages with a capacity of 4ml, 5ml, 10ml, and so on. They are administrated in an intravenous (IV), intramuscular (IM), and subcutaneous (SC) manner. All injectable solutions need to undergo a pre-formulation stage. In this stage, many physical and chemical parameters of the drug are evaluated for the suitability of the drug to be formulated as an injectable dosage form to comply with the new drug applications. They are commonly used to deliver medications, vaccines, or fluids directly into the bloodstream or body tissues and stored according to cGMP guidelines.

Keywords : Injectable Solutions, Parenteral, Pyrogen-Free Particulate, Medicines.

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