A Comprehensive Overview of Rare Initial Presentation of SIADH in Small Cell Lung Cancer


Authors : Dr. Mohamed Ayub Sulaiman.H; Dr. Nagarajan.K

Volume/Issue : Volume 9 - 2024, Issue 7 - July

Google Scholar : https://tinyurl.com/yc4bph3c

Scribd : https://tinyurl.com/29supf45

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUL346

Abstract : SIADH a condition where anti-diuretic hormone (ADH) is secreted in the absence of appropriate physiological stimuli. SIADH mostly characterized by hypotonic, euvolemic hyponatremia with urinary hyperosmolarity. SIADH is a well-known paraneoplastic syndrome frequently linked with small-cell lung cancer (SCLC).

References :

  1. Huber RM, Tufman A. Update on small cell lung cancer management. Breathe. 2012;8:314–330. doi: 10.1183/20734735.013211
  2. Nikoomanesh, K., Choi, J. & Arabian, S. Paraneoplastic syndrome as the presentation of limited stage small cell carcinoma. BMC Pulm Med 18, 169 (2018). https://doi.org/10.1186/s12890-018-0729-y
  3. Gandhi L, Johnson BE. Paraneoplastic syndromes associated with small cell lung cancer. J Natl Compr Canc Netw 4: 631-638, 2006
  4. A F List et al., The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in small-cell lung cancer. JCO 4, 1191-8(1986). DOI:10.1200/JCO.1986.4.8.1191

SIADH a condition where anti-diuretic hormone (ADH) is secreted in the absence of appropriate physiological stimuli. SIADH mostly characterized by hypotonic, euvolemic hyponatremia with urinary hyperosmolarity. SIADH is a well-known paraneoplastic syndrome frequently linked with small-cell lung cancer (SCLC).

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