Authors :
Dr. Pujari Harika; Dr. Sharada
Volume/Issue :
Volume 8 - 2023, Issue 1 - January
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3kx8B0A
DOI :
https://doi.org/10.5281/zenodo.7677980
Abstract :
A comparative study of intrathecal plain bupivacaine
versus bupivacaine added with midazolam for
subarachnoid block in lower limb surgeries and lower
abdominal surgeries .
Methodology
Patients were randomized as 30 patients each into two
groups. Group ‘B’ - received 3.5 ml of 0.5% hyperbaric
bupivacaine + 0.4 ml of 0.9% saline intrathecally. Group
‘BM’ - received 3.5 ml of 0.5%hyperbaric bupivacaine +
0.4 ml preservative free midazolam(5mg/ml) intrathecally.
Results
The sensory blockade onset in group- BM was 165.76
sec and in group-B was 189.30 sec. The results were
statistically highly significant (P-value<0.05).
Conclusion
Based on the above study, the combination of 2mg
preservative free midazolam and 0.5% hyperbaric
bupivacaine for subarachnoid block in lower limb
surgeries and lower abdominal surgeries prolonged the
duration of effective analgesia as compared to plain
bupivacaine and delays requirement of post operative
analgesia . Intrathecal midazolam at a dose of 2 mg have
no clinically significant effects on perioperative
haemodynamics
A comparative study of intrathecal plain bupivacaine
versus bupivacaine added with midazolam for
subarachnoid block in lower limb surgeries and lower
abdominal surgeries .
Methodology
Patients were randomized as 30 patients each into two
groups. Group ‘B’ - received 3.5 ml of 0.5% hyperbaric
bupivacaine + 0.4 ml of 0.9% saline intrathecally. Group
‘BM’ - received 3.5 ml of 0.5%hyperbaric bupivacaine +
0.4 ml preservative free midazolam(5mg/ml) intrathecally.
Results
The sensory blockade onset in group- BM was 165.76
sec and in group-B was 189.30 sec. The results were
statistically highly significant (P-value<0.05).
Conclusion
Based on the above study, the combination of 2mg
preservative free midazolam and 0.5% hyperbaric
bupivacaine for subarachnoid block in lower limb
surgeries and lower abdominal surgeries prolonged the
duration of effective analgesia as compared to plain
bupivacaine and delays requirement of post operative
analgesia . Intrathecal midazolam at a dose of 2 mg have
no clinically significant effects on perioperative
haemodynamics