Authors :
S. Revathi
Volume/Issue :
Volume 11 - 2026, Issue 7 - July
Google Scholar :
https://tinyurl.com/mr5wbex8
Scribd :
https://tinyurl.com/34z4y4b2
DOI :
https://doi.org/10.38124/ijisrt/26jul1833
Note : A published paper may take 4-5
working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and
ResearchGate.
Abstract :
Burkitt’s lymphoma (BL) is a highly aggressive mature B- cells, non- Hodgkin lymphomas in childhood, a type of
White Blood Cells. Other names of this condition include Burkitt’s disease, Burkitt’s lymphoma and Burkitt’s tumor. It typically
starts in lymph nodes of abdomen or pelvis later causes diffuse skeletal involvement with extensive extra nodal disease and may
initially a mimic metastatic solid tumor such as primitive neuro ectodermal tumor (PNET). I had seen a case of 4 year child in
community who is underweight with intermittent fever since 5 days, poor appetite, extreme fatigue, running nose, and weak cry
and less active since 5 days. Initially the child was treated with antibiotic assuming to have some bacterial infection in a private
hospital for 3 days. As the child had persisting illness and abdominal pain further evaluation was performed. A whole body PET
scan revealed to have extensive intensely hypermetabolic skeletal lesions involving cervical, thoracic, lumbar vertebrae, pelvis,
ribs, skull, scapulae, humerus and femoral part. MRI scan demonstrated multifocal lesions, raising suspicion of metastatic
malignancy. Histopathological examination with immunohistochemistry confirmed Burkitt’s lymphoma. The child was
subsequently referred to a tertiary care hospital where the child had 6 months of chemotherapy and the child had favorable
response, highlighting the importance of early diagnosis and timely management in improving outcome in pediatric Burkitt’s
lymphoma.
Keywords :
Burkitt’s Lymphoma, Non- Hodgkin’s Lymphoma, Childhood Malignancy, Chemotherapy.
References :
- Kliegman, R. M., St. Geme, J. W., Blum, N. J., Shah, S. S., Tasker, R. C., & Wilson, K. M. (Eds.). (2024). Nelson textbook of pediatrics (22nd ed.). Elsevier.
- Hockenberry, M. J., Wilson, D., & Rodgers, C. C. (2024). Wong's nursing care of infants and children (12th ed.). Elsevier.
- Dr. Balaji Thiruvengadam Kothandan, Dhaarani Jayaraman, Julius Xavier Scott ,Radha Thiyagarajan , Latha M Sneha ,Sandhya Sundaram. (2025). Profile of children with Non-Hodgkin’s lymphoma in a single centre experience from South India - A retrospective descriptive study. Journal of Contemporary Clinical Practice, 11(12) ,557 – 566.
- Nirmal, G., Thankamony, P., Nair, R. A., Nair, M., Rajeswari, B., Guruprasad, C. S., Prasanth, V. R., Jacob, P. M., & Krishna, K. M. J. (2025). Resource-adapted strategies in the management of paediatric Burkitt lymphoma in low- and middle-income country setting and outcomes: An Indian centre experience. British journal of haematology, 206(6), 1710–1718.
- National Cancer Institute. Childhood Non-Hodgkin Lymphoma Treatment (PDQ®). National Cancer Institute. Updated 2024.
Burkitt’s lymphoma (BL) is a highly aggressive mature B- cells, non- Hodgkin lymphomas in childhood, a type of
White Blood Cells. Other names of this condition include Burkitt’s disease, Burkitt’s lymphoma and Burkitt’s tumor. It typically
starts in lymph nodes of abdomen or pelvis later causes diffuse skeletal involvement with extensive extra nodal disease and may
initially a mimic metastatic solid tumor such as primitive neuro ectodermal tumor (PNET). I had seen a case of 4 year child in
community who is underweight with intermittent fever since 5 days, poor appetite, extreme fatigue, running nose, and weak cry
and less active since 5 days. Initially the child was treated with antibiotic assuming to have some bacterial infection in a private
hospital for 3 days. As the child had persisting illness and abdominal pain further evaluation was performed. A whole body PET
scan revealed to have extensive intensely hypermetabolic skeletal lesions involving cervical, thoracic, lumbar vertebrae, pelvis,
ribs, skull, scapulae, humerus and femoral part. MRI scan demonstrated multifocal lesions, raising suspicion of metastatic
malignancy. Histopathological examination with immunohistochemistry confirmed Burkitt’s lymphoma. The child was
subsequently referred to a tertiary care hospital where the child had 6 months of chemotherapy and the child had favorable
response, highlighting the importance of early diagnosis and timely management in improving outcome in pediatric Burkitt’s
lymphoma.
Keywords :
Burkitt’s Lymphoma, Non- Hodgkin’s Lymphoma, Childhood Malignancy, Chemotherapy.