Authors :
Nithyakala P; Saranya R; Shruthi D; Priyadarshini P; Roja M K; Samyuktha D V
Volume/Issue :
Volume 8 - 2023, Issue 7 - July
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/4pms6knx
DOI :
https://doi.org/10.5281/zenodo.8170795
Abstract :
The majority of men who develop penile
cancer are in their sixth decade of life. The most common
histology is squamous cell carcinoma (SCC), and about
half of the cases are thought to be influenced by human
papillomavirus (HPV) infection. Few therapeutic choices
are available to patients with serious illnesses, and their
prognosis is still grim. Risk factors for PSCC (HPV)
include phimosis, chronic inflammation, poor penile
hygiene, smoking, immunosuppression, and circumcision
in children. Accurate and early surgical staging of the
inguinal lymph nodes is crucial for disease management
due to the early lymphatic dissemination that separates
PSCC from other malignancies and the limitations of
imaging to detect micrometastatic sickness. Localized
and advanced penile cancers, as well as their treatment,
have a major impact on patients' and survivors' quality
of life since they impair sexual and urinary function and
produce lymphoedema. Rare cancer known as PSCC has
been given the orphan disease designation.
Keywords :
Penile cancer, Human papillomavirus (HPV), Squamous cell carcinoma (SSC)
The majority of men who develop penile
cancer are in their sixth decade of life. The most common
histology is squamous cell carcinoma (SCC), and about
half of the cases are thought to be influenced by human
papillomavirus (HPV) infection. Few therapeutic choices
are available to patients with serious illnesses, and their
prognosis is still grim. Risk factors for PSCC (HPV)
include phimosis, chronic inflammation, poor penile
hygiene, smoking, immunosuppression, and circumcision
in children. Accurate and early surgical staging of the
inguinal lymph nodes is crucial for disease management
due to the early lymphatic dissemination that separates
PSCC from other malignancies and the limitations of
imaging to detect micrometastatic sickness. Localized
and advanced penile cancers, as well as their treatment,
have a major impact on patients' and survivors' quality
of life since they impair sexual and urinary function and
produce lymphoedema. Rare cancer known as PSCC has
been given the orphan disease designation.
Keywords :
Penile cancer, Human papillomavirus (HPV), Squamous cell carcinoma (SSC)
