Authors : Dr. Tatireddy Sai Sindhu; Dr. Vijay G. Somannavar

Volume/Issue : Volume 10 - 2025, Issue 2 - February

---

Google Scholar : https://tinyurl.com/yy3s5y79

Scribd : https://tinyurl.com/ptf8x2e2

DOI : https://doi.org/10.5281/zenodo.14964533

---

Abstract : Anti-phospholipid syndrome (APS) is an autoimmune-mediated thrombophilia characterized by recurrent thrombotic events, particularly affecting young adults. It is linked to the presence of anti-phospholipid antibodies that interfere with normal coagulation pathways, leading to abnormal blood clot formation. This case report discusses a rare occurrence of APS in a middle-aged male who presented with recurrent deep vein thrombosis (DVT). Comprehensive diagnostic evaluation, management strategies, and follow-up protocols are elaborated to provide insights into this complex clinical entity.

References :

1. Harrison’s Internal Medicine, 22nd Edition.
2. Asherson RA, The Anti-Phospholipid Syndrome, 2003.
3. Erkan D, et al. Clinical Manifestations of APS, 2004.
4. Miyakis S, et al. International Consensus Statement on APS, 2006.