Authors :
Ominya S. Zaky; Mashael M. Barqi; Entesar A. Hassan
Volume/Issue :
Volume 8 - 2023, Issue 10 - October
Google Scholar :
https://tinyurl.com/352khmsv
Scribd :
https://tinyurl.com/5azattp6
DOI :
https://doi.org/10.5281/zenodo.10047082
Abstract :
Reaction of dimethyl-2-(2-thien-2-yl-2-
thioxoethylidene)-1,3-dithiole-4,5-dicarb- oxylate 1 and
1-(4-(1H-indol-3-yl)-6-methyl-2-thioxo-1,2,3,4-
tetrahydropyrimidin-5-yl)-3,3-dimercaptoprop-2-en-1-
one 10 respectively with transition metal salts, e.g.
NaAuCl4.2H2O, NiCl2.6H2O, CoCl2 and HgCl2 furnished
the C-S-Metal complexes in a simple and a satisfactory
manner. These complexes were screened as antimicrobial
agents against a number of important bacteria such as
Bacillus subtilus, Staphylococcus and Lactococcus and
gave remarkable and observed inhibition zones.
Keywords :
Oxoketene Gem-Dithiol, Metal Complexes, Ampicillin, Amphotericin, Sugar Manufacture, Biological Activities.
Reaction of dimethyl-2-(2-thien-2-yl-2-
thioxoethylidene)-1,3-dithiole-4,5-dicarb- oxylate 1 and
1-(4-(1H-indol-3-yl)-6-methyl-2-thioxo-1,2,3,4-
tetrahydropyrimidin-5-yl)-3,3-dimercaptoprop-2-en-1-
one 10 respectively with transition metal salts, e.g.
NaAuCl4.2H2O, NiCl2.6H2O, CoCl2 and HgCl2 furnished
the C-S-Metal complexes in a simple and a satisfactory
manner. These complexes were screened as antimicrobial
agents against a number of important bacteria such as
Bacillus subtilus, Staphylococcus and Lactococcus and
gave remarkable and observed inhibition zones.
Keywords :
Oxoketene Gem-Dithiol, Metal Complexes, Ampicillin, Amphotericin, Sugar Manufacture, Biological Activities.
